Added: Stacia Samora - Date: 04.12.2021 08:24 - Views: 24109 - Clicks: 6739
Objective: Over-the-counter OTC anti-cough preparations, many of which contain codeine an opioid or dextromethorphan an opioid-likeare widely available in Taiwan and thus susceptible to overuse or abuse. We aimed to investigate whether opioids in the form of OTC antitussives play a ificant role in medication abuse in Taiwan.
Methods: Data on the consumption of codeine and dextromethorphan in antitussives and expectorants from through in Taiwan were provided by IMS Health Intercontinental Marketing Services. These data were then analyzed for trends What cough syrups contain codeine variance according to availability, as prescription or OTC, and according to drug type, as codeine or dextromethorphan, in order to form four primary sectors under opioid-containing anti-cough syrup consumption.
Within the underlying sectors, mean consumption for prescription dextromethorphan However, movement in consumption corresponded mainly with OTC codeine, whose variance greatly exceeded that of the other sectors, which follow in order of decreasing variance as OTC dextromethorphan, prescription dextromethorphan, and prescription codeine. Conclusion: The fairly low and stable consumption of prescription codeine suggested that physicians in Taiwan were careful in prescribing codeine, and that the medical demand for codeine was stable. The large variance in OTC codeine consumption suggested that a minority of consumers purchased ificant quantities of codeine for non-medical purposes.
Although opioids in cough syrup were not a large part of overall consumption and thus not widely abused, the data revealed that OTC codeine-containing cough syrup may serve as an indicator of potential drug abuse in the population as compared to prescription codeine.
Keywords: antitussive agents; codeine; dextromethorphan; drug abuse; opioids. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. Search: Search.
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Create a file for external citation management software Create file Cancel. of items displayed: 5 10 15 20 50 Create RSS Cancel. RSS Link Copy. Full text links Cite Display options Display options. Abstract Objective: Over-the-counter OTC anti-cough preparations, many of which contain codeine an opioid or dextromethorphan an opioid-likeare widely available in Taiwan and thus susceptible to overuse or abuse.
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Smith SM, et al. Cough, codeine and confusion. O Reilly D, et al. BMJ Case Rep. Misuse of non-prescription codeine containing products: Recommendations for detection and reduction of risk in community pharmacies. Van Hout MC, et al. Int J Drug Policy.
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Epub Mar 2. Humans Actions. Taiwan Actions. Substances Antitussive Agents Actions. Nonprescription Drugs Actions. Dextromethorphan Actions. Codeine Actions. Full text links [x] Elsevier Science. Copy Download.What cough syrups contain codeine
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Codeine consumption from over-the-counter anti-cough syrup in Taiwan: A useful indicator for opioid abuse